Chlorpheniramine and hydrocodone

  • Brand Name : Tussionex
  • Drug Class : Antitussives, Narcotic Combos
  • Medical Author : Dr. Vinod Katiboina, Pharm. D.
  • Medical Reviewer : Sarfaroj Khan, BHMS, PGD Health Operations
  • _eael_post_view_count : 8

What Are Chlorpheniramine and hydrocodone and How Does It Work?

Chlorpheniramine and hydrocodone are combination prescription medications used to treat runny noses, sneezing, itching, watery eyes, and cough caused by allergies, the common cold, or the flu. 

  • Chlorpheniramine and hydrocodone are available under various brand names: Tussicaps, Tussionex pennkinetic

What Are Side Effects Associated with Using Chlorpheniramine and hydrocodone?

Common side effects of Chlorpheniramine and hydrocodone include:

  • Trouble breathing.
  • Drowsiness.
  • Confusion.
  • Nausea, vomiting; or
  • Little or no urination.

Serious side effects of Chlorpheniramine and hydrocodone include:

  • Hives. 
  • Difficult breathing. 
  • Swelling of the face, lips, tongue, or throat.
  • Severe drowsiness.
  • Noisy breathing, sighing, shallow breathing.
  • Severe constipation.
  • A light-headed feeling,
  • A slow heart rate or weak pulse.
  • Confusion; or
  • Adrenal gland problems–nausea, vomiting, loss of appetite, dizziness, feeling weak or tired.
  • Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

Rare side effects of Chlorpheniramine and hydrocodone include:

  • None

Seek medical care or call 911 at once if you have the following serious side effects:

  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.
  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights.
  • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out.

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

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