- Brand Name : Nimbex
- Drug Class : Skeletal Muscle Relaxants
- Medical Author : Sarfaroj Khan, BHMS, PGD Health Operations
- Medical Reviewer :
- _eael_post_view_count : 8
Brand Name: Nimbex
Generic Name: Cisatracurium
Drug Class: Neuromuscular Blockers, Nondepolarizing
What Is Cisatracurium and How Does It Work?
Cisatracurium is a prescription medication used for neuromuscular blockade as an adjunct to general anesthesia to facilitate tracheal intubation or skeletal muscle relaxation during surgery.
- Cisatracurium is available under the following different brand names: Nimbex.
What Are Dosages of Cisatracurium?
Adult and pediatric dosage
Injectable solution
- 2mg/mL (multidose vial)
- Contains benzyl alcohol
- The injectable solution, preservative-free
- 2mg/mL (single-dose vial)
- 10mg/mL (single-dose vial)
Neuromuscular Blockade
Adult dosage
Initial dose
- In conjunction with propofol or thiopental/nitrous oxide/oxygen induction technique.
- 0.15-0.2 mg/kg IV bolus initially
- Doses up to 0.4 mg/kg IV bolus have been safely administered to healthy patients and patients with serious cardiovascular disease
Maintenance dose, intermittent
- 0.03 mg/kg IV bolus; start 40-50 minutes (after initial dose of 0.15 mg/kg) or 50-60 minutes (after initial dose of 0.2 mg/kg)
Maintenance dose, continuous infusion
- Infuse at 3 mcg/kg/minute initially; subsequently, reduce the rate to 1-2 mcg/kg/minutes to maintain the neuromuscular blockade
Tracheal Intubation
Pediatric dosage
- Children 1 month-23 months: 0.15 mg/kg IV bolus
- Children 2-12 years: 0.1-0.15 mg/kg IV bolus
Skeletal Muscle Relaxation During Surgery
Pediatric dosage
- Indicated for children aged 2 years or older
- Infuse at 3 mcg/kg/minute initially; subsequently, reduce the rate to 1-2 mcg/kg/min to maintain the neuromuscular blockade
Dosage Considerations – Should be Given as Follows:
- See “Dosages”.