Colesevelam

  • Brand Name : Welchol
  • Drug Class : Bile Acid Sequestrants
  • Medical Author : Divya Jacob, Pharm. D.
  • Medical Reviewer : Sarfaroj Khan, BHMS, PGD Health Operations
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What Is Colesevelam and How Does It Work?

Colesevelam is a prescription medication used to treat hyperlipidemia and to improve glycemic control in adults with type 2 diabetes mellitus

  • Colesevelam is available under the following different brand names: WelChol 

What Are Dosages of Colesevelam?

Adult and pediatric dosage

Tablet

  • 625mg

Powder for oral suspension

  • 3.75g/packet

Hyperlipidemia

Adult dosage

  • Tablet: 1.875 g (3 tablets) orally every 12 hours or 3.75 g (6 tablets) orally once a day
  • Oral suspension: 1.875 g (½ packet) orally every 12 hours or 3.75 g (1 packet) orally once a day

Type 2 Diabetes Mellitus

Adult dosage

  • Tablet: 1.875 g (3 tablets) orally every 12 hours or 3.75 g (6 tablets) orally once a day
  • Oral suspension: 1.875 g (½ packet) orally every12hr or 3.75 g (1 packet) orally once a day

Heterozygous Familial Hypercholesterolemia

Pediatric dosage

  • Children below 10 years: Safety and efficacy not established
  • Children between 10-17 years
  • Tablet: 1.875 g (3 tablets) orally every 12 hours or 3.75 g (6 tablets) orally once a day
  • Oral suspension: 1.875 g (½ packet) orally every12hour or 3.75 g (1 packet) orally once a day
  • Due to tablet size, the oral suspension is recommended for use in the pediatric population

Dosage Considerations – Should be Given as Follows: 

  • See “Dosages”

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