Desvenlafaxine

  • Brand Name : Pristiq
  • Drug Class : Antidepressants, SNRIs
  • Medical Author : Divya Jacob, Pharm. D.
  • Medical Reviewer : Sarfaroj Khan, BHMS, PGD Health Operations
  • _eael_post_view_count : 7

What Is Desvenlafaxine and How Does It Work?

Desvenlafaxine is a prescription medication used for the treatment of the major depressive disorder.

  • Desvenlafaxine is available under the following different brand names: Pristiq, Khedezla (DSC)

What Are Dosages of Desvenlafaxine?

Adult dosage

Tablet, extended-release

Pristiq

  • 25mg (contains 38 mg of desvenlafaxine succinate)
  • 50mg (contains 76 mg of desvenlafaxine succinate)
  • 100mg (contains 152 mg of desvenlafaxine succinate) 

Major Depressive Disorder

Adult dosage

  • 50 mg orally every day
  • Higher dosages, up to 400 mg/day, have been used but no additional benefit was demonstrated at doses greater than 50mg/day; increased side effects have been reported

Dosage Considerations – Should be Given as Follows

  • See “Dosages”

What Are Side Effects Associated with Using Desvenlafaxine?

Common side effects of Desvenlafaxine include:

  • dizziness,
  • drowsiness,
  • anxiety,
  • increased sweating,
  • nausea,
  • decreased appetite,
  • constipation,
  • sleep problems (insomnia),
  • decreased sex drive,
  • impotence, and
  • difficulty having an orgasm

Serious side effects of Desvenlafaxine include:

  • convulsion (seizure),
  • easy bruising or bleeding (nosebleeds, bleeding gums),
  • blood in the urine or stools,
  • coughing up blood,
  • blurred vision,
  • eye pain or swelling,
  • seeing halos around lights,
  • cough,
  • chest discomfort,
  • trouble breathing,
  • headache,
  • confusion,
  • severe weakness,
  • memory problems,
  • feeling unsteady, and
  • hallucinations

Rare side effects of Desvenlafaxine include:

  • none 

This is not a complete list of side effects and other serious side effects or health problems may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

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