- Brand Name : Duagen
- Drug Class : 5-Alpha-Reductase Inhibitors
- Medical Author : John P. Cunha, DO, FACOEP
- Medical Reviewer :
- _eael_post_view_count : 9
What Is Dutasteride and How Does It Work?
Dutasteride is a synthetic 4-azasteroid compound that is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5 alpha-reductase used to treat benign prostatic hyperplasia (BPH) in men with an enlarged prostate. Dutasteride helps improve urinary flow and may also reduce the need for prostate surgery later. Dutasteride is sometimes given with another medication called tamsulosin (Flomax). Dutasteride prevents the conversion of testosterone to dihydrotestosterone (DHT) in the body.
- Dutasteride is available under the following different brand names: Avodart.
What Are Dosage of Dutasteride?
Dosage of Dutasteride:
Dosage Forms and Strengths
Capsule
- 0.5 mg
Dosing Considerations – Should be Given as Follows:
Benign Prostatic Hyperplasia
- 0.5 mg orally once/day
Dosing Modifications
- Renal impairment: Dose adjustment not necessary
- Hepatic impairment: Dose adjustment not necessary
- Pediatric: Safety and efficacy not established