Edaravone

  • Brand Name : Radicava
  • Drug Class : Neurologics, Other
  • Medical Author : John P. Cunha, DO, FACOEP
  • Medical Reviewer :
  • _eael_post_view_count : 8

What Is Edaravone Used For and How Does it Work?

Edaravone is used to treat amyotrophic lateral sclerosis (ALS).

Edaravone is available under the following different brand names: Radicava.

What Are the Dosages of Edaravone?

Dosage Forms and Strengths

Solution for IV Infusion

  • 30 mg/100mL in a single-dose polypropylene bag

Dosage Considerations – Should be Given as Follows:

Amyotrophic Lateral Sclerosis

  • Indicated for amyotrophic lateral sclerosis (ALS)
  • Initial treatment cycle: Administer 60 mg as an intravenous (IV) infusion over 60 minutes once daily for 14 days, followed by a 14-day drug-free period
  • Subsequent treatment cycles: Administer 60 mg as an IV infusion once daily over 60 minutes on 10 of 14 days, followed by a 14-day drug-free period

Dosage Modifications

Renal impairment

  • No dose adjustment needed
  • Not studied, but not expected to significantly affect the systemic drug exposure

Hepatic impairment

  • Mild or moderate: No dose adjustment is needed
  • Severe: Not studied; no specific dosing recommendation can be provided

Safety and efficacy not established in pediatric patients.

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