- Brand Name : Radicava
- Drug Class : Neurologics, Other
- Medical Author : John P. Cunha, DO, FACOEP
- Medical Reviewer :
- _eael_post_view_count : 8
What Is Edaravone Used For and How Does it Work?
Edaravone is used to treat amyotrophic lateral sclerosis (ALS).
Edaravone is available under the following different brand names: Radicava.
What Are the Dosages of Edaravone?
Dosage Forms and Strengths
Solution for IV Infusion
- 30 mg/100mL in a single-dose polypropylene bag
Dosage Considerations – Should be Given as Follows:
Amyotrophic Lateral Sclerosis
- Indicated for amyotrophic lateral sclerosis (ALS)
- Initial treatment cycle: Administer 60 mg as an intravenous (IV) infusion over 60 minutes once daily for 14 days, followed by a 14-day drug-free period
- Subsequent treatment cycles: Administer 60 mg as an IV infusion once daily over 60 minutes on 10 of 14 days, followed by a 14-day drug-free period
Dosage Modifications
Renal impairment
- No dose adjustment needed
- Not studied, but not expected to significantly affect the systemic drug exposure
Hepatic impairment
- Mild or moderate: No dose adjustment is needed
- Severe: Not studied; no specific dosing recommendation can be provided
Safety and efficacy not established in pediatric patients.