Empagliflozin-Linagliptin

  • Brand Name : Glyxambi
  • Drug Class : Antidiabetics, Dipeptyl Peptidase-IV Inhibitors, Antidiabetics, SGLT2 Inhibitors
  • Medical Author : Divya Jacob, Pharm. D.
  • Medical Reviewer : Sarfaroj Khan, BHMS, PGD Health Operations
  • _eael_post_view_count : 11

What Is Empagliflozin/Linagliptin and How Does It Work?

Empagliflozin/Linagliptin is a combination prescription medication used for treating the symptoms of type 2 diabetes mellitus.

  • Empagliflozin/Linagliptin is available under the following different brand names: Glyxambi

What Are Dosages of Empagliflozin/Linagliptin?

Adult dosage

Tablet

  • 10mg/5mg
  • 25mg/5mg

Type 2 Diabetes Mellitus

Adult and geriatric dosage

  • 10 mg/5 mg orally every day in the morning, taken with or without food
  • The dose may be increased to 25 mg/5mg once daily if needed and tolerated

Dosage Considerations – Should be Given as Follows: 

  • See “Dosages”

What Are Side Effects Associated with Using Empagliflozin/Linagliptin?

Common side effects of Empagliflozin/Linagliptin include:

Serious side effects of Empagliflozin/Linagliptin include:

  • severe or ongoing pain in your joints;
  • serious skin reaction–itching, blisters, breakdown of the outer layer of skin;
  • ketoacidosis (too much acid in the blood)–nausea, vomiting, stomach pain, confusion, unusual drowsiness, or trouble breathing;
  • pancreatitis–severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
  • dehydration symptoms–dizziness, weakness, feeling light-headed (like you might pass out);
  • signs of a bladder infection–pain or burning when you urinate, blood in your urine, pain in the pelvis or back; or
  • symptoms of heart failure–shortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain.

Rare side effects of Empagliflozin/Linagliptin include:

  • none 

This is not a complete list of side effects and other serious side effects or health problems that may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

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