Eptifibatide

  • Brand Name : Integrilin
  • Drug Class : , Glycoprotein IIb/IIIa Inhibitors
  • Medical Author : Nazneen Memon, BHMS, PGDCR
  • Medical Reviewer : Divya Jacob, Pharm. D.
  • _eael_post_view_count : 10

What Is Eptifibatide and How Does It Work?

Eptifibatide is a prescription medication used for the treatment of acute coronary syndrome (ACS) managed medically or with percutaneous coronary intervention (PCI) and for the treatment of patients undergoing PCI (including intracoronary stenting).

  • Eptifibatide is available under the following different brand names: Integrilin

What Are Dosages of Eptifibatide?

Adult dosage

Injection solution

  • 2mg/mL
  • 0.75mg/mL

Acute Coronary Syndrome

Adult and geriatric dosage

  • 180 mcg/kg IV bolus over 1-2 min, THEN
  • 2 mcg/kg/min IV continuous infusion; continue infusion until hospital discharge or the initiation of coronary artery bypass graft surgery (CABG), up to 72 hours
  • Patient to undergo PCI: infusion should be continued until hospital discharge or for up to 18- 24 hours after the procedure, whichever comes first, allowing for up to 96 hours of therapy
  • Administer aspirin (160-325 mg) daily

Percutaneous Coronary Intervention

Adult and geriatric dosage

  • 180 mcg/kg IV bolus immediately, THEN
  • Continuous infusion 2 mcg/kg/min with another 180 mcg/kg IV bolus 10 minutes after 1st bolus
  • Continue infusion until hospital discharge, or for up to 18 to 24 hours, whichever comes first; minimum 12 hr infusion recommended
  • In patients who undergo CABG surgery, drug infusion should be discontinued before surgery
  • Administer aspirin, 160 to 325 mg, 1 to 24 hours before PCI and daily thereafter

Dosage Considerations – Should be Given as Follows: 

  • See “Dosages”

Add to cart