Ertapenem

  • Brand Name : Invanz
  • Drug Class : Carbapenems
  • Medical Author : Sarfaroj Khan, BHMS, PGD Health Operations
  • Medical Reviewer :
  • _eael_post_view_count : 7

What Is Ertapenem and How Does It Work?

Ertapenem is a prescription medication used to treat the symptoms of Community-Acquired Pneumonia, Complicated urinary Tract Infections (including Pyelonephritis), Acute Pelvic Infections, Complicated Intra-abdominal Infections, and Complicated Skin or Skin Structure Infections.

  • Ertapenem is available under the following different brand names: Invanz

What Are Dosages of Ertapenem?

Adult and Pediatric dosage

Powder for injection

  • 1g/vial

Community-Acquired Pneumonia

Adult dosage: 

  • 1 g/day IV/IM up to 14 days; after 3 or more days of parenteral therapy, may be switched to appropriate oral regimen if patient improves clinically

Pediatric dosage

  • Children younger than 3 months of age: safety and efficacy not established
  • Children 3 months-12 years: 15 mg/kg IV/IM every 12 hours up to 14 days; not to exceed 1g every 12 hours; after 3 or more days of parenteral therapy, may be switched to appropriate oral regimen if patient improves clinically
  • Children older than 12 years of age: 1 g/day IV/IM up to 14 days; after 3 or more days of parenteral therapy, may be switched to appropriate oral regimen if patient improves clinically 

Complicated Urinary Tract Infections (Including Pyelonephritis)

Adult dosage

  • 1 g/day IV/IM up to 14 days; after 3 or more days of parenteral therapy, may be switched to appropriate oral regimen if patient improves clinically

Pediatric dosage

  • Children younger than 3 months of age: safety and efficacy not established
  • Children 3 months-12 years: 15 mg/kg IV/IM every 12 hours up to 14 days; not to exceed 1g every 12 hours; after 3 or more days of parenteral therapy, may be switched to appropriate oral regimen if patient improves clinically
  • Children older than 12 years of age: 1 g/day IV/IM up to 14 days; after 3 or more days of parenteral therapy, may be switched to appropriate oral regimen if patient improves clinically 

Acute Pelvic Infections

Adult dosage

  • 1 g/day IV/IM for 3-10 days

Pediatric dosage

  • Children younger than 3 months of age: safety and efficacy not established
  • Children 3 months-12 years: 15 mg/kg IV/IM every 12 hours for 3-10 days
  • Children older than 12 years of age: 1 g/day IV/IM for 3-10 days 

Complicated Intra-abdominal Infections

Adult dosage

  • 1 g/day IV/IM for 5-14 days

Pediatric dosage

  • Children younger than 3 months of age: safety and efficacy not established
  • Children 3 months-12 years: 15 mg/kg IV/IM every 12 hours for 5-14 days
  • Children older than 12 years of age: 1 g/day IV/IM for 5-14 days 

Complicated Skin/Skin Structure Infections

Adult dosage

  • 1 g/day IV/IM for 7-14 days; may be continued up to 4 weeks for diabetic foot infections, depending on severity of infection and response to therapy and response to therapy (treatment excludes diabetic foot infections with osteomyelitis)

Pediatric dosage

  • Children younger than 3 months of age: safety and efficacy not established
  • Children 3 months-12 years: 15 mg/kg IV/IM every 12 hours for 7-14 days; may be continued up to 4 weeks for diabetic foot infections, depending on severity of infection and response to therapy (treatment excludes diabetic foot infection with osteomyelitis) 
  • Children older than 12 years of age: 1 g/day IV/IM up to 7-14 days; may be continued up to 4 weeks for diabetic foot infections, depending on severity of infection and response to therapy (treatment excludes diabetic foot infections with osteomyelitis) 

Dosage Considerations – Should be Given as Follows: 

  • See “Dosages.”

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