- Brand Name : Enbrel
- Drug Class : Antipsoriatics, Systemic, DMARDs, TNF Inhibitors
- Medical Author : Nazneen Memon, BHMS, PGDCR
- Medical Reviewer : Divya Jacob, Pharm. D.
- _eael_post_view_count : 11
What Is Etanercept and How Does It Work?
Etanercept is a prescription medicine used to treat the symptoms of ankylosing spondylitis, rheumatoid arthritis, psoriatic arthritis, plaque psoriasis, and juvenile rheumatoid arthritis.
What Are Dosages of Etanercept?
Adult and pediatric dosage
Injection solution, prefilled syringe
- 25mg/0.5mL (Enbrel, Erelzi, Eticovo)
- 50mg/mL (Enbrel, Erelzi, Eticovo)
Injection solution, prefilled autoinjector
- 50mg/mL (Enbrel, Erelzi)
Injection, lyophilized powder for reconstitution
- 25mg/vial (Enbrel)
Injection, prefilled single-dose prefilled cartridge with reusable autoinjector
- 50mg/mL (Enbrel Mini)
Biosimilars to Enbrel
Erelzi (etanercept-szzs)
Eticovo (etanercept-ykro)
- Ankylosing Spondylitis
- Adult dosage
- 50 mg SC once weekly
- Rheumatoid Arthritis
- Adult dosage
- 50 mg SC once weekly
- Psoriatic Arthritis
- Adult dosage
- 50 mg SC once weekly
- Plaque Psoriasis
- Adult dosage
- Initial: 50 mg SC twice weekly for 3 months
- Maintenance: 50 mg SC once weekly
- Pediatric dosage
- Children below 4 years: Safety and efficacy not established
- Children above 4 years:
- Less than 63 kg
Enbrel only
- 0.8 mg/kg SC weekly; not to exceed 50 mg weekly
- More than 63 kg
Enbrel, Eticovo, Erelzi
- 50 mg SC weekly
Juvenile Rheumatoid Arthritis
Pediatric dosage
- Children below 2 years: Safety and efficacy not established
- Children above 2 years (less than 63 kg):
- Less than 63 kg
Enbrel only
- 0.8 mg/kg SC weekly; not to exceed 50 mg weekly
- More than 63 kg
Enbrel, Erelzi, Eticovo
- 50 mg SC weekly
- Glucocorticoids, NSAIDs, or analgesics may be continued during treatment
Dosage Considerations – Should be Given as Follows:
- See “Dosages”