Fostemsavir

  • Brand Name : Rukobia
  • Drug Class : HIV, Attachment Inhibitors
  • Medical Author : Dr. Vinod Katiboina, Pharm. D.
  • Medical Reviewer : Divya Jacob, Pharm. D.
  • _eael_post_view_count : 9

What Is Fostemsavir and How Does It Work?

Fostemsavir is a prescription medication used in combination with other antiretroviral drugs for the treatment of HIV-1 infection in heavily treatment-experienced adults with multidrug-resistant HIV-1 infection failing their current antiretroviral treatment regimen owing to resistance, intolerance, or safety considerations. 

  • Fostemsavir is available under the following different brand names: Rukobia.

What Are Side Effects Associated with Using Fostemsavir?

Common side effects of Fostemsavir include:

  • nausea
  • diarrhea
  • headache
  • abdominal pain
  • indigestion/heartburn
  • fatigue
  • rash
  • sleep disturbance
  • immune reconstitution inflammatory syndrome
  • drowsiness
  • vomiting

Serious side effects of Fostemsavir include:

  • hives
  • difficult breathing 
  • swelling of the face, lips, tongue, or throat
  • fast/irregular heartbeat
  • severe dizziness
  • faintings

Rare side effects of Fostemsavir include:

  • none 

Seek medical care or call 911 at once if you have the following serious side effects:

  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, coordination loss, unsteady, very stiff muscles, high fever, profuse sweating, or tremors.
  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights.
  • Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out.

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

What Are the Dosages of Fostemsavir?

Adult dosage

Tablet, extended-release

  • 600 mg

HIV Infection

Adult dosage

  • 600 mg orally two times a day

Dosage Considerations – Should be Given as Follows: 

  • See “Dosages”

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