- Brand Name : Lytgobi
- Drug Class : Antineoplastic Tyrosine Kinase Inhibitors
- Medical Author : Divya Jacob, Pharm. D.
- Medical Reviewer : Sarfaroj Khan, BHMS, PGD Health Operations
- _eael_post_view_count : 11
What Is Futibatinib and How Does It Work?
Futibatinib is a prescription medication used for previously treated, unresectable, locally advanced or metastatic intrahepatic cholangiocarcinoma in adults harboring fibroblast growth factor receptor 2 (FGFR2) gene fusions or other rearrangements.
- Futibatinib is available under the following different brand names: Lytgobi
What Are Side Effects Associated with Using Futibatinib?
Common side effects of Futibatinib include:
- nail toxicity
- musculoskeletal pain
- constipation
- diarrhea
- fatigue
- dry mouth
- hair loss
- stomatitis
- abdominal pain
- dry skin
- joint pain
- changes in taste
- dry eye
- nausea
- decreased appetite
- urinary tract infection (UTI)
- palmar–plantar erythrodysesthesia syndrome
- vomiting
- increased phosphate
- increased creatinine
- decreased hemoglobin
- increased glucose
- increased calcium
- decreased sodium
- decreased phosphate
- increased alanine aminotransferase
- increased alkaline phosphatase
- decreased lymphocytes
- increased aspartate aminotransferase
- decreased platelets
- increased activated partial thromboplastin time
- decreased leukocytes
- decreased albumin
- decreased neutrophils
- increased creatine kinase
- increased bilirubin
- decreased glucose
- increased prothrombin international normalized ratio
- decreased potassium
Serious side effects of Futibatinib include:
- hives
- difficulty breathing
- swelling of the face, lips, tongue, or throat
- vision loss
- reduced color vision
- blurry vision
- blind spot in the visual field
- muscle cramps or spasms
- numbness and tingling around the mouth
- bone and joint pain
- weak bones
- rash
- itching
- fever
- black or tarry stool
- vomiting blood
- abdominal cramping
- dizziness
- lightheadedness
- tiredness
- paleness
- shortness of breath
- fluid in the abdomen
- musculoskeletal pain
- bone calluses
- difficulty swallowing
- chest pain
- burning sensation in the mouth
- abdominal pain (upper right side)
- dark urine
- yellowing of the skin and the whites of the eyes (jaundice)
- nausea
- vomiting
- clay-colored stools
- dizziness
- weakness
- loss of appetite
- swelling in the ankles and legs
- fatigue
Rare side effects of Futibatinib include:
- none
Seek medical care or call 911 at once if you have the following serious side effects:
- Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
- Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
- Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out.
This is not a complete list of side effects and other serious side effects or health problems that may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.