Lumateperone

  • Brand Name : Caplyta
  • Drug Class : Serotonin-Dopamine Activity Modulators (SDAM)
  • Medical Author : Divya Jacob, Pharm. D.
  • Medical Reviewer : Sarfaroj Khan, BHMS, PGD Health Operations
  • _eael_post_view_count : 9

What Is Lumateperone and How Does It Work?

Lumateperone is a prescription medication used to treat the symptoms of schizophrenia and bipolar disorder in adults.

  • Lumateperone is available under the following different brand names: Caplyta

What Are Dosages of Lumateperone?

Adult dosage

Capsule

  • 10.5mg
  • 21mg
  • 42mg

Schizophrenia

Adult dosage

  • 42 mg orally once a day

Bipolar Disorder

Adult dosage

  • 42 mg orally once a day

Dosage Considerations – Should be Given as Follows: 

  • See “Dosages”

What Are Side Effects Associated with Using Lumateperone?

Common side effects of Lumateperone include:

  • drowsiness,
  • dry mouth,
  • nausea,
  • dizziness,
  • increased creatine phosphokinase,
  • fatigue,
  • vomiting,
  • increased liver transaminases, and
  • decreased appetite

Serious side effects of Lumateperone include:

  • feeling unsteady,
  • uncontrolled muscle movements in the face (chewing, lip smacking, frowning, tongue movement, blinking, or eye movement);
  • tightness in the neck or throat, trouble swallowing;
  • trouble breathing or speaking;
  • a seizure;
  • high blood sugar–increased thirst, increased urination, dry mouth, fruity breath odor;
  • low white blood cell counts–fever, chills, mouth sores, skin sores, sore throat, cough, trouble breathing; or
  • severe nervous system reaction–very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, light-headedness.

Rare side effects of Lumateperone include:

  • None

This is not a complete list of side effects and other serious side effects or health problems that may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

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