Methadone

  • Brand Name : Dolophine
  • Drug Class : Opioid Agonists
  • Medical Author : Sarfaroj Khan, BHMS, PGD Health Operations
  • Medical Reviewer :
  • _eael_post_view_count : 9

What Is Methadone and How Does It Work?

Methadone is a prescription medication used for the management of severe pain. 

What Are Dosages of Methadone?

Adult dosage

Injectable solution: Schedule II

  • 10 mg/mL

Tablet: Schedule II

  • 5 mg
  • 10 mg

Dispersible tablet: Schedule II

  • 40 mg

Oral solution: Schedule II

  • 5 mg/5 mL
  • 10 mg/5 mL

Oral concentrate solution: Schedule II

  • 10 mg/mL

Pain Management

Adult dosage

  • Opioid-naive patients: 2.5 mg orally every 8-12 hours; titrate slowly to dose increases no more frequent than every 3-5 days

Detoxification

Adult dosage

  • 20-30 mg orally once daily or minimum dosage necessary to suppress withdrawal; may be titrated to 40 mg/day in divided doses and continued for 2-3 days, then decreased 20% daily as tolerated

Dosage Considerations – Should be Given as Follows: 

  • See “Dosages”.

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