- Brand Name : Provayblue
- Drug Class : Antidotes, Other
- Medical Author : Sarfaroj Khan, BHMS, PGD Health Operations
- Medical Reviewer :
- _eael_post_view_count : 8
What Is Methylene Blue and How Does It Work?
Methylene Blue is a prescription medication used to treat Acquired Methemoglobinemia.
- Methylene Blue is available under the following different brand name: Provayblue.
What Are Dosages of Methylene Blue?
Adult and pediatric dosage
Injectable solution
- 5mg/mL (50mg/10mL) single-dose ampule
Acquired Methemoglobinemia
Adult dosage
- 1 mg/kg IV over 5-30 minutes
- If methemoglobin level remains over 30% or if clinical symptoms persist, repeat dose up to 1 mg/kg 1 hour after the first dose
Pediatric dosage
- 1 mg/kg IV over 5-30 minutes
- If methemoglobin level remains over 30% or if clinical symptoms persist, repeat dose up to 1 mg/kg 1 hour after the first dose
Dosage Considerations – Should be Given as Follows:
- See “Dosages.”
What Are Side Effects Associated with Using Methylene Blue?
Common side effects of Methylene Blue include:
- pain in the arms or legs,
- blue or green urine,
- altered sense of taste,
- headache,
- dizziness,
- sweating,
- skin discoloration,
- nausea, and
- feeling hot
Serious side effects of Methylene Blue include:
- hives,
- difficulty breathing,
- swelling of the face, lips, tongue, or throat,
- confusion,
- weakness,
- pale or yellow skin,
- dark colored urine,
- fever,
- agitation,
- hallucinations,
- fast heart rate,
- overactive reflexes,
- nausea,
- vomiting,
- diarrhea,
- loss of coordination, and
- fainting
Rare side effects of Methylene Blue include:
- none
This is not a complete list of side effects and other serious side effects or health problems may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.