Microbiota Oral

Microbiota Oral is used to prevent the recurrence of Clostridioides difficile infection (CDI) in adults following antibacterial treatment for recurrent CDI (rCDI).

• Microbiota Oral is available under the following different brand names: Vowst, fecal microbiota spores, live-brpk.

Common side effects of Microbiota Oral include:

• Abdominal pain,
• Diarrhea,
• Abdominal distention,
• Gas (flatulence), and
• Nausea.

Serious side effects of Microbiota Oral include:

• Hives,
• Difficulty breathing,
• Swelling of the face, lips, tongue, or throat

Rare side effects of Microbiota Oral include:

• none 

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, coordination loss, unsteady, very stiff muscles, high fever, profuse sweating, or tremors.
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights.
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out.

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Adult dosage

Capsule

• 1×106 – 3×107 Firmicutes spore colony forming units/capsule.

Clostridioides difficile Infection

Adult dosage

• 4 capsules oral once a day for 3 consecutive days

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”