- Brand Name : Zavesca
- Drug Class : Enzyme Inhibitors
- Medical Author : Dr. Vinod Katiboina, Pharm. D.
- Medical Reviewer : Divya Jacob, Pharm. D.
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What Is Miglustat and How Does It Work?
Miglustat is a prescription medication used as monotherapy for the treatment of mild-to-moderate type 1 Gaucher disease in adults for whom enzyme replacement therapy is not a therapeutic option.
- Miglustat is available under the following different brand names: Zavesca.
What Are Side Effects Associated with Using Miglustat?
Common side effects of Miglustat include:
- flatulence
- constipation
- bloating
- nausea
- vomiting
- stomach pain
- indigestion
- loss of appetite
- weight loss
- dry mouth
- dizziness
- weakness
- headache (including migraine)
- back pain
- muscle cramps
- leg cramps
- pain or heavy feeling in the arms or legs
- memory problems
- feeling unsteady
- loss of balance
- burning pain in the hands or feet
- vision problems
- changes in the menstrual periods
Serious side effects of Miglustat include:
- hives
- difficulty breathing
- swelling of the face, lips, tongue, or throat
- tremor or uncontrolled shaking (especially in the hands)
- numbness or tingling in the hands or feet
- burning pain in the hands or feet
- severe diarrhea
- weight loss
- easy bruising
- unusual bleeding (nosebleeds, bleeding gums).
Rare side effects of Miglustat include:
- none
Seek medical care or call 911 at once if you have the following serious side effects:
- Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, coordination loss, unsteady, very stiff muscles, high fever, profuse sweating, or tremors.
- Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights.
- Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out.
This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.