Milrinone

  • Brand Name : Primacor IV
  • Drug Class : Inotropic Agents
  • Medical Author : Sarfaroj Khan, BHMS, PGD Health Operations
  • Medical Reviewer :
  • _eael_post_view_count : 7

What Is Milrinone and How Does It Work?

Milrinone is a prescription medication used to treat Congestive Heart Failure.  

  • Milrinone is available under the following different brand names: Primacor IV

Dosages of Milrinone:

Adult dosage

Infusion solution, in D5W

  • 20mg/100mL
  • 40mg/200mL

Injectable solution

  • 1mg/mL

Congestive Heart Failure

Adult dosage

  • 50 mcg/kg loading dose by IV push over 10 minutes, then 0.375-0.75 mcg/kg/min IV
  • Maintenance: 1.13 mg/kg/day

Dosage Considerations – Should be Given as Follows: 

  • See “Dosages.”

What Are Side Effects Associated with Using Milrinone?

Common side effects of Milrinone include:

  • headache, 
  • chest pain, and
  • dizziness

Serious side effects of Milrinone include:

  • hives, 
  • difficulty breathing, 
  • swelling of the face, lips, tongue, or throat, and
  • chest pain, 
  • lightheadedness
  • leg cramps, 
  • constipation, 
  • irregular heartbeats, 
  • fluttering in your chest, 
  • increased thirst or urination, 
  • numbness or tingling, and
  • muscle weakness or limp feeling

Rare side effects of Milrinone include:

  • none 

This is not a complete list of side effects and other serious side effects or health problems may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

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