- Brand Name : Myrbetriq
- Drug Class : Beta3 Agonists
- Medical Author : Sarfaroj Khan, BHMS, PGD Health Operations
- Medical Reviewer :
- _eael_post_view_count : 8
What Is Mirabegron and How Does It Work?
Mirabegron is a prescription medication used to treat an Overactive Bladder (OAB).
- Mirabegron is available under the following different brand names: Myrbetriq.
What Are Dosages of Mirabegron?
Adult and pediatric dosage
Tablet, extended-release
- 25mg
- 50mg
Pediatric dosage
- Granules for extended-release oral suspension
- 8mg/mL after reconstitution
Overactive Bladder
Adult dosage
Monotherapy
- 25 mg orally once daily
- 25 mg dose is typically effective within 8 weeks
- May increase to 50 mg orally once daily based on individual efficacy and tolerability
- Combination with muscarinic antagonist
- Combination regimen: 25 mg orally once daily plus solifenacin succinate 5 mg orally once daily
- May increase mirabegron to 50 mg orally once daily after 4-8 weeks based on individual efficacy and tolerability
Neurogenic Detrusor Overactivity
Pediatric dosage
- Children younger than 3 years of age: Safety and efficacy not established
- Children 3 years or older, weight less than 35 kg:
- Granules for oral suspension
- 11 kg to less than 22 kg: 24 mg (3mL) orally once daily initially; may increase to maximum of 48 mg/day (6 mL)
- 22 kg to less than 35 kg: 32 mg (4mL) orally once daily initially; may increase to maximum of 64 mg/day (8 mL)
- Children 3 years or older, weight more than 35 kg:
- Tablets: 25 mg orally once daily initially; may increase to maximum of 50 mg/day after 4-8 weeks
- Granules for oral suspension: 48 mg (6 mL) orally once daily initially; may increase to maximum of 80 mg/day (10mL) after 4-8 weeks
Dosage Considerations – Should be Given as Follows:
- See “Dosages.”