- Brand Name : Remeron
- Drug Class : Antidepressants, Tetracyclic, Appetite Stimulants, Antidepressants, Alpha-2 Antagonists, Antidepressants, Other
- Medical Author : John P. Cunha, DO, FACOEP
- Medical Reviewer :
- _eael_post_view_count : 9
What Is Mirtazapine and How Does It Work?
Mirtazapine is indicated for the treatment of a major depressive disorder.
Mirtazapine is available under the following different brand names: Remeron, and Remeron SolTab.
What Are Dosages of Mirtazapine?
Dosages of Mirtazapine:
Adult and Pediatric Dosage Forms & Strengths
Tablet
- 7.5 mg
- 15 mg
- 30 mg
- 45 mg
Disintegrating tablet
- 15 mg
- 30 mg
- 45 mg
Dosage Considerations – Should be Given as Follows:
Depression
- Adult: 15 mg orally at bedtime; may increase no more frequently than every 1-2 weeks; not to exceed 45 mg at bedtime
- Geriatric: 7.5 mg/day orally at bedtime; increase by 7.5-15 mg/day no more frequently than every 1-2 weeks; not to exceed 45 mg/day
Alzheimer Dementia-related Depression, Geriatric
- 7.5 mg/day orally at bedtime; increase by 7.5-15 mg/day no more frequently than every 1-2 weeks; not to exceed 60 mg/day
Post-traumatic Stress Disorder (Off-label)
- 15 mg orally at bedtime; may increase no more frequently than every 1-2 weeks; not to exceed 60 mg at bedtime
Hot Flashes (Off-label)
- 7.5-60 mg orally once/day
Insomnia (Off-label)
- 15-45 mg orally at bedtime
Dosing Modifications
- Renal impairment (CrCl less than 39 mL/min): Clearance is reduced; monitor closely
- Hepatic impairment: Clearance is reduced; monitor closely
Dosing Considerations
- Pediatric: Safety and efficacy not established
- Geriatric: The elderly have reduced clearance of mirtazapine and, as a result, may have increased plasma levels of the drug. Use with caution