- Brand Name : Lysodren
- Drug Class : Antineoplastics, Other
- Medical Author : Dr. Vinod Katiboina, Pharm. D.
- Medical Reviewer : Divya Jacob, Pharm. D.
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What Is Mitotane and How Does It Work?
Mitotane is a prescription medication used to treat cancer of the adrenal gland (adrenal cortical carcinoma).
- Mitotane is available under the following different brand names: Lysodren
What Are Side Effects Associated with Using Mitotane?
Common side effects of Mitotane include:
- Dizziness,
- Spinning sensation (vertigo),
- Drowsiness,
- Tiredness,
- Nausea,
- Vomiting,
- Diarrhea,
- Loss of appetite,
- Headache,
- Unusual weakness,
- Depression, or
- Skin rash.
Serious side effects of Mitotane include:
- Severe dizziness,
- Flushing,
- Fast or pounding heartbeat,
- Shakiness (tremors),
- Unusual or rapid weight loss,
- Change in skin color or thickness,
- Easy bleeding or bruising,
- Breast tenderness or enlargement (males),
- Unwanted facial or body hair (females),
- Mental/mood changes (e.g., depression, irritability, difficulty concentrating, confusion),
- Speech problems,
- Numbness or tingling of hands or feet,
- Unsteadiness,
- Pink urine, or
- Vision problems.
Rare side effects of Mitotane include:
- none
Seek medical care or call 911 at once if you have the following serious side effects:
- Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
- Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
- Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out
This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.