Momelotinib

Momelotinib is a prescription medication indicated for intermediate or high-risk myelofibrosis (MF), including primary MF or secondary MF [post polycythemia vera and post essential thrombocythemia], in adults with anemia

• Momelotinib is available under the following different brand names: Ojjaara

Common side effects of Momelotinib include:

• diarrhea 
• nausea
• low platelet count 
• dizziness 
• bleeding 
• bacterial infection
• tiredness

Serious side effects of Momelotinib include:

• risk of infections – hepatitis B
• low platelet and white blood cell count
• liver problems include- tiredness, dark urine, loss of appetite, yellowing of the skin or the white part of your eyes, pain in the right upper stomach area (abdomen)
• blood clots include swelling, pain, or tenderness in one or both legs, sudden, unexplained chest pain, shortness of breath, or difficulty breathing

Rare side effects of Momelotinib include:

• none 

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, coordination loss, unsteady, very stiff muscles, high fever, profuse sweating, or tremors.
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights.
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out.

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Adult dosage

Tablet

• 100 mg
• 150 mg
• 200 mg

Myelofibrosis

Adult dosage

• 200 mg orally once a day with or without food

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”