- Brand Name : Movantik
- Drug Class : Opioid Antagonists
- Medical Author : Divya Jacob, Pharm. D.
- Medical Reviewer : Sarfaroj Khan, BHMS, PGD Health Operations
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What Is Naloxegol and How Does It Work?
Naloxegol is a prescription medication used to treat opioid-induced constipation.
- Naloxegol is available under the following different brand names: Movantik
What Are Side Effects Associated with Using Naloxegol?
Common side effects of Naloxegol include:
- stomach/abdominal pain,
- diarrhea,
- nausea,
- gas (flatulence),
- vomiting,
- headache,
- increased or excessive sweating, chills,
- anxiety, or
- yawning
Serious side effects of Naloxegol include:
- severe or worsening stomach pain and diarrhea
- rash;
- hives;
- swelling of the face, lips, throat, tongue, hands, or feet
Rare side effects of Naloxegol include:
- none
This is not a complete list of side effects and other serious side effects or health problems that may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.
What Are Dosages of Naloxegol?
Adult dosage
Tablet
- 12.5mg
- 25mg
Opioid-Induced Constipation
Adult dosage
- 25 mg orally once a day in the morning; give at least an hour before meals or 2 hours after meals
- Decrease dose to 12.5 mg/day if the patient is unable to tolerate 25 mg/day
Dosage Considerations – Should be Given as Follows:
- See “Dosages”