- Brand Name : Tysabri
- Drug Class : Inflammatory Bowel Disease Agents, Monoclonal Antibodies, Integrin Blockers
- Medical Author : Dr. Vinod Katiboina, Pharm. D.
- Medical Reviewer : Divya Jacob, Pharm. D.
- _eael_post_view_count : 8
What Is Natalizumab and How Does It Work?
Natalizumab is a prescription medication used to treat relapsing forms of multiple sclerosis. It is also used to treat moderate to severe Crohn’s disease in adults.
- Natalizumab is available under the following different brand names: Tysabri
What Are Side Effects Associated with Using Natalizumab?
Common side effects of Natalizumab include:
- Headache,
- Tired feeling,
- Joint or muscle pain,
- Redness or irritation at the injection site,
- Swelling hands/feet/ankles,
- Changes in the menstrual cycle,
- Stomach pain,
- Diarrhea,
- Skin rash,
- Depression,
- Painful menstrual cramps, or
- Cold symptoms such as stuffy nose, sneezing, or sore throat.
Serious side effects of Natalizumab include:
- Hives
- Itching
- Trouble breathing
- Chest pain and dizziness
- Wheezing
- Chills
- Rash
- Nausea
- Flushing of skin
- Low blood pressure
- Infections.
- Low platelet counts.
- Easy bruising
- Heavier menstrual periods than are normal
- Bleeding from the gums or nose that is new or takes longer than usual to stop
- Small scattered red spots on your skin that are red, pink, or purple
- Bleeding from a cut that is hard to stop.
Rare side effects of Natalizumab include:
- none
Seek medical care or call 911 at once if you have the following serious side effects:
- Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
- Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
- Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out.
This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.