- Brand Name : Danyelza
- Drug Class : Antineoplastics, Anti-GD2 Monoclonal Antibodies
- Medical Author : Divya Jacob, Pharm. D.
- Medical Reviewer : Sarfaroj Khan, BHMS, PGD Health Operations
- _eael_post_view_count : 6
What Is Naxitamab and How Does It Work?
Naxitamab is a prescription medication used in combination with granulocyte macrophage colony-stimulating factor (GM-CSF), for relapsed or refractory high-risk neuroblastoma in the bone or bone marrow in patients who have demonstrated a partial response, minor response, or stable disease with prior therapy.
- Naxitamab is available under the following different brand names: Danyelza, naxitamab-gqgk
What Are Side Effects Associated with Using Naxitamab?
Common side effects of Naxitamab include:
- infusion-related reactions occurring on the day of infusion or the day following an infusion (low blood pressure, bronchospasm, flushing, wheezing, stridor, hives, shortness of breath, fever, swelling of the face/lips/tongue, respiratory tract edema, chills, low blood oxygen, itching, and rash)
- pain (abdominal pain, pain in extremities, bone pain, neck pain, back pain, and musculoskeletal pain)
- fast heart rate
- vomiting
- cough
- nausea
- diarrhea
- decreased appetite
- high blood pressure (hypertension)
- fatigue
- erythema multiforme
- numbness and tingling of extremities
- hives not occurring on the day of infusion or the day following an infusion
- fever not occurring on the day of infusion or the day following an infusion
- headache
- injection site reaction
- fluid retention (edema)
- anxiety
- localized swelling
- irritability
- decreased lymphocytes
- decreased neutrophils
- decreased hemoglobin
- decreased platelet count
- decreased potassium
- increased alanine aminotransferase
- decreased glucose
- decreased calcium
- decreased albumin
- decreased sodium
- decreased phosphate
Serious side effects of Naxitamab include:
- none
Rare side effects of Naxitamab include:
- none
Seek medical care or call 911 at once if you have the following serious side effects:
- Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
- Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
- Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out.
This is not a complete list of side effects and other serious side effects or health problems that may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.