Nicotine Intranasal

  • Brand Name : Nicotrol NS
  • Drug Class : Smoking Cessation Aids
  • Medical Author : John P. Cunha, DO, FACOEP
  • Medical Reviewer :
  • _eael_post_view_count : 7

What Is Nicotine Intranasal and How Does It Work?

Nicotine intranasal is used for nicotine replacement therapy to reduce withdrawal symptoms during smoking cessation.

Nicotine intranasal is available under the following different brand names: Nicotrol NS.

What Are the Dosages of Nicotine Intranasal?

Dosages of Nicotine Intranasal:

Dosage Forms and Strengths

Intranasal Spray

  • 0.5mg/actuation

Dosage Considerations – Should be Given as Follows:

Smoking Cessation

  • Nicotine replacement therapy to reduce withdrawal symptoms during smoking cessation
  • 1 spray/nostril (i.e., 2 sprays to provide 1 mg/dose); typically 10-12 sprays/day in each nostril as needed
  • Initiate with 1-2 doses/hour; for greatest success, instruct patient to use at least 8 doses/day initially
  • Depending on individual addiction; may increase up to a maximum dose of 40 mg (80 sprays/day)

Administration

  • Tilt the head back when administering
  • Do not sniff, swallow, or inhale through the nose as the spray is being administered
  • Safety and efficacy not established in pediatric patients

What Are Side Effects Associated with Using Nicotine Intranasal?

Common side effects of nicotine intranasal include:

  • Local irritation
  • Anxiety
  • Irritability
  • Restlessness
  • Cravings
  • Dizziness
  • Impaired concentration
  • Weight gain
  • Mood swings
  • Drowsiness/sleepiness and fatigue
  • Increased sweating
  • Insomnia
  • Confusion
  • Depression
  • Apathy
  • Tremor
  • Increased appetite
  • Incoordination
  • Increased dreaming

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Nicotine Intranasal?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Nicotine intranasal has no listed severe interactions with other drugs.
Nicotine intranasal has no listed serious interactions with other drugs.
 

Moderate interactions of nicotine intranasal include:

  • adenosine
  • cimetidine
  • esketamine intranasal
  • green tea
  • naphazoline
  • oxymetholone
  • phenylephrine nasal
  • propylhexedrine
  • solriamfetol
  • varenicline
  • xylometazoline

Mild interactions of nicotine intranasal include:

  • bupropion
  • dihydroergotamine
  • dihydroergotamine intranasal
  • niacin
  • rose hips

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

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