- Brand Name : Ofev
- Drug Class : Pulmonary, Tyrosine Kinase Inhibitors, Pulmonary Tyrosine Kinase Inhibitors
- Medical Author : Sarfaroj Khan, BHMS, PGD Health Operations
- Medical Reviewer :
- _eael_post_view_count : 6
Brand Name: Ofev
Generic Name: Nintedanib
Drug Class: Pulmonary, Tyrosine Kinase Inhibitors
What Is Nintedanib and How Does It Work?
Nintedanib is a prescription medication used to treat Idiopathic Pulmonary Fibrosis, Chronic Fibrosing Interstitial Lung Diseases with a Progressive Phenotype, and Systemic Sclerosis-associated Interstitial Lung Disease
- Nintedanib is available under the following different brand names: Ofev.
What Are Dosages of Nintedanib?
Dosages of Nintedanib:
Adult dosage
Capsule
- 100mg
- 150mg
Idiopathic Pulmonary Fibrosis
- 150 mg orally every 12 hours
Chronic Fibrosing Interstitial Lung Diseases with a Progressive Phenotype
- 150 mg orally every 12 hours
Systemic Sclerosis-associated Interstitial Lung Disease
- 150 mg orally every 12 hours
Dosage Considerations – Should be Given as Follows:
- See “Dosages”.
What Are Side Effects Associated with Using Nintedanib?
Common side effects of Nintedanib include:
- nausea,
- vomiting,
- loss of appetite,
- stomach pain,
- diarrhea,
- weight loss,
- increased blood pressure,
- headache, and
- abnormal liver function tests
Serious side effects of Nintedanib include:
- hives,
- difficulty breathing,
- swelling of the face, lips, tongue, or throat,
- severe ongoing nausea,
- vomiting,
- diarrhea,
- severe stomach pain,
- abdominal bloating,
- stomach tenderness,
- bleeding from the rectum,
- blood in stools,
- easy bruising,
- unusual bleeding,
- any wound that will not heal,
- fever,
- chills,
- cough with mucus,
- chest pain,
- shortness of breath,
- chest pain or pressure,
- pain spreading to the jaw or shoulder,
- nausea,
- sweating,
- stomach pain (upper right side),
- loss of appetite,
- tiredness,
- dark urine,
- yellowing of the skin or eyes (jaundice),
- sudden numbness or weakness (especially on one side of the body),
- slurred speech, and
- problems with vision or balance
Rare side effects of Nintedanib include:
- none
This is not a complete list of side effects and other serious side effects or health problems may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.