Sat Overseas > Norepinephrine

Norepinephrine

  • Brand Name : Levophed
  • Drug Class : Alpha/Beta Adrenergic Agonists
  • Medical Author : John P. Cunha, DO, FACOEP
  • Medical Reviewer :
  • _eael_post_view_count : 6

What Is Norepinephrine Used For?

Norepinephrine is indicated for blood pressure control in certain acute hypotensive states (e.g., pheochromocytomectomy, sympathectomy, poliomyelitis, spinal anesthesia, myocardial infarction, septicemia, blood transfusion, and drug reactions).

  • Norepinephrine is also indicated as an adjunct in the treatment of cardiac arrest and profound hypotension.
  • Norepinephrine is available under the following different brand names: Levarterenol, and Levophed.

What Are Dosages of Norepinephrine?

Dosages of Norepinephrine:

Adult and Pediatric Dosage Forms and Strengths

Injectable solution

  • 1 mg/mL

Dosage Considerations – Should be Given as Follows:

Acute Hypotension

Adult

  • Initial: 8-12 mcg/minute intravenous (IV) infusion; titrate to effect
  • Maintenance: 2-4 mcg/minute IV infusion

Pediatric

  • Initial: 0.05-0.1 mcg/kg/minute intravenous (IV) infusion; titrate to effect
  • Maximum: 1-2 mcg/kg/minute

Cardiac Arrest

Adult

  • Initial: 8-12 mcg/minute intravenous (IV) infusion; titrate to effect
  • Maintenance: 2-4 mcg/minute IV infusion

Pediatric

  • Initial: 0.05-0.1 mcg/kg/minute intravenous (IV) infusion; titrate to effect
  • Maximum: 1-2 mcg/kg/minute

Sepsis and Septic Shock

  • Adult: 0.01-3 mcg/kg/minute intravenous (IV) infusion
  • Pediatric: 0.05-0.1 mcg/kg/minute IV infusion; titrate to effect; not to exceed 2 mcg/kg/minute

Beta Blocker Toxicity (Off-label)

  • Should be titrated to age-appropriate blood pressure

Calcium Channel Blocker Toxicity (Off-label)

  • Should be titrated to age-appropriate blood pressure

Tricyclic Antidepressant Toxicity (Off-label)

  • Should be titrated to age-appropriate blood pressure

Add to cart